صفحه محصول - پاورپوینت آزمون هاي عملكرد تيروئيد

پاورپوینت آزمون هاي عملكرد تيروئيد (pptx) 64 اسلاید

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تعداد اسلاید: 64 اسلاید

قسمتی از متن PowerPoint (.pptx) :

آزمون هاي عملكرد تيروئيد (Thyroid Function test) TRANSITIONS FROM EUTHYROIDISM TO HYPOTHYROIDISM OR HYPERTHYROIDISM N = normal, ↓=decreased, ↑ = increased WHAT IS NORMAL? THAT WHAT IS NOT ABNORMAL intelligence quotient 80 100 120 POPULATION-BASED TSH REFERENCE VALUES SKEWED AT THE UPPER END no normal distribution of serum TSH >95% had TSH <2.5 mU/l in reference population of NHANES III TSH mU/L کم کاری تيروييد نوزادان Causes of Congenital Hypothyroidism Developmental defects 1 every 4000 newborns; In Iran >1/1000 Complete absence of thyroid tissue Failure of thyroid to descend properly during embryologic development Route of descent (foramen caecum at the junction of anterior two thirds and posterior third of tongue to normal site or below) Biosynthetic defects in the thyroid Pituitary or hypothalamic failure Family with mutation in gene coding TSH β subunit Genetic causes of congenital hypothyroidism Pescovitz OH, Eugster EA, Pediatric Endocrinology, 2004 Thyroid disorders and their approximate prevalence in the neonatal period Thyroid dysgenesis >1:1000-1:4000 Agenesis Hypogenesis Ectopia Thyroid dyshormonogenesis 1:40,000 Thyroid-stimulating hormone unresponsiveness Iodide trapping defect Organification defect Defect in thyroglobulin Iodotryrosine deiodinase deficiency Transient hypothyroidism 1:40,000 Drug induced Maternal antibody induced Idiopatic Hypothalamic-pituitary hypothyroidism 1:100,000 Hypothalamic-pituitary anomaly Panhypopituitarism Isolated thyroid-stimulating hormone deficiency Thyroid hormone resistance